Comparison of ceftriaxone and traditional therapy of bacterial meningitis

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Comparison of ceftriaxone and ampicillin plus chloramphenicol for the therapy of acute bacterial meningitis.

Ceftriaxone, a new third-generation cephalosporin, appears to be promising for the therapy of acute bacterial meningitis. The 90% MBCs of ceftriaxone against 54 recent cerebrospinal fluid isolates of Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae were less than or equal to 0.06 to 0.25 micrograms/ml. We examined the efficacy and safety of ceftriaxone therapy of men...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1984

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.25.1.40